Coming from PICO-8 myself, I'm wondering if I should just skip the frameworks to babystep and just jump into C+SDL, or pygame or something. I like the different ways that games can be made -- like your procedural graphics not needing a graphics library.
I'm torn between "all of this stuff belongs in the kernel goddammit" and "these guys probably know better". OpenBSD and macOS actually force all syscalls to go through a dynamically linked libc, so perhaps it's the latter.
Libraries/frameworks/engines such as PICO-8, Love2d, SDL, Allegro, Pygame, Godot, etc exist precisely to abstract away these details; you're not meant to care for libGL.so.1, you're meant to care for fixing your physics engine's timestep and using cubic splines to interpolate animation. Love2d was not a mature choice in 2016, so don't take my horror story or my hubris as any indication of what it looks like today; do your own research and pick the tool for the job ;)
TBH I would love to go back to making games, but recently got too absorbed by StarCraft 2 and shitposting.