I have good hopes for some disruptions to arrive on the web via wasm. There are some interesting things happening in that space that are increasingly less about Javascript, dom trees, css, and all the limitations that come with those and more about leveling the playing field with mobile where UIs are more competitive and non Javascript frameworks seem to be preferred over the poor man's choice (aka. web based).
I'm saying that as somebody actually pushing web based on mobile (we are about to release a PWA). Just acknowledging the reality that web-based is still considered a huge compromise on ux, performance, and capabilities on mobile. Good enough is the best you can say about it. Some of those mobile frameworks (flutter, compose web, and others) are now coming to the web via wasm. IMHO, there are a lot more interesting things that could be done in that space in the next years.
Obviously a lot of these techniques are pretty novel, and maybe they won't stand the test of time. Or maybe a new browser standard will make them obsolete eventually. But for now these seem to be the current wave anyway.
(I mainly work on native desktop apps, but can use JS if needed.)