The point of this blog post was totally lost on me. I can’t even say it is a critique of the practice of medicine - or maybe therapeutic development (?) - because literally every example given by the author is a solution rather than a problem.

Also the author clearly does not know what they are talking about. For example, them calling for the use of surrogate endpoints - they clearly did not know the term of the art - when a whole regulatory framework around this concept has already been developed, formalized, and implemented!

To me the piece has a mix of smugness, hubris, and gross ignorance that would make for truly masterful work trolling if I did not believe the author were sincere.