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Comment by LinuxBender | Hacker News Reader

Maybe I'm too chicken to receive someone elses poo but I took what I consider to be the more scientifically controlled middle ground, mixing large amounts of probiotics with MCT oil and using it rectally. 36 strains, about 2 trillion CFU. To my surprise I have found several doctors that love this idea and one that also does it. It's not as diverse and that is exactly why I do it. I know what cultures I am getting and what benefits each one has.

Or maybe I have discovered a fetish.

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Do you mind sharing how you decided which 36 strains to include and what they are? Bonus points for links to studies (or articles with good references).

I plan to add a health section to my awful blog. That is where I would be linking to the list of cultures and links to the benefits and risks for each one. If you want to read up on which formula I am currently using ahead of time it is here [1] and if you mouse over the images one of them lists which strains they use. I alternate between them and a couple of other blends. Most of the strains have some studies on nih.gov which is best searched using google with "site:nih.gov probiotic culture_name benefits"

[1] - https://www.amazon.com/NewRhythm-Probiotics-Digestive-Prebio...

Have you done actual GI / microbiome tests before and after to see any cause/effect? Sounds a bit extreme when you could just follow the 4 K's of Kefir, Kombucha, Kimchi, and Kraut over a long period of time.

Have you done actual GI / microbiome tests

I have not. I can not find any labs that I can trust and that have not been hacked on a regular basis.

Sounds a bit extreme

It may be. I reset my gut bacteria some years ago and use this to improve the overall gut-scape. The 4 K's are great but my personal preference is to use this method that if for no other reason it is banned by WADA. If they consider it cheating then I like it that much more.

https://humanmicrobiome.info/testing/

Fascinating, hadn't heard of MCT nor rectal administration of probiotics (save for FMT).

Do you get them in pills and then mix it with coconut oil or what? (Or does it need to be pure MCT)

I open the capsules and mix them. I've tried to get the company to sell me a bag or can of the probiotics but they won't do it. Not a big deal though, it doesn't take long to open them. I just use the large containers of coconut MCT oil. If there is something that would be better for the bacteria and for the large intestine cells I would love to know.

Heh they're probably scared you'll start selling the ass formula!

Hurry up and trademark that.

Whats your benefit from this? Do you credit it with any GI improvements?

Benefits:

- Bypass the stomach acid, preserving more bacteria

- Keep the bacteria out of the small intestine mostly to avoid SIBO and avoid having to chase the probiotics with Betaine hcl, Ginger root, digestive enzymes, etc... to keep the small intestine clear which can trigger inflammation. Also not having to pre-coat the small intestine with cranberry molecules to cover any section that is missing the mucous layer.

- Feed the colon and large intestine cells MCT oil without having to consume it.

- Anecdotally I feed better for several days after doing this. I can do faster power-walks for longer. I do not run to protect my cartilage.

- The only GI improvement that I can feel is the lack of discomfort from taking large amounts of probiotics orally.

- Very large amounts taken orally can result in small amounts making it past the intestine cell junctions and triggering a small immune response which may have both positive and negative ramifications but that's a much bigger topic.

- Less likely to disturb the mucous layer.

Drawbacks:

- To be useful requires a large amount of bacteria and that requires a large amount of MCT oil and getting into positions to get it up into the large intestine. Well ... it has to come out some time and being liquid one must stay near the restroom. There's no holding it in. Some kind of paste injector tube would be better, probably something similar in form factor and design as the vaginal yeast infection treatments perhaps. If this were a product I would buy it even though it would be harder to get it into the large intestine.

- The first few hours after can feel weird as the body has to adjust.

Have you attempted to mechanically stopper yourself during this process to increase the treatment duration?

I have not. Just guessing but I think it might have to be custom made or uncomfortably tight. Maybe others have done this. The doctor I know that does this makes these little frozen things in a custom freezer tray meant for enemas.

Check Amazon, there are a zillion shapes and materials to explore.

Wouldn't the oil just lube it up so it would eventually get shot out like a bottle rocket?

Another challenge with this is that the formula I use has prebiotics so it's just a matter of time before gas builds up and things could get painful. I will likely just stick with my method of staying near the restroom.

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