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The faster available shutter speeds will compensate for the faster base ISO except where the superior dynamic range of a lower ISO is needed or when a longer shutter speed is simultaneously desired.

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Well to be fair if the base ISO is 250, even the typical 1/8000 will be enough for most purposes except maybe f/1.2 in sunlight....

True that, unless you also want slower shutter speed for some reason. But that's pretty rare.

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