A nice little Quality Of Life improvement for me with uBlock Origin recently has been using it top block Confluence's pop ups when someone has commented on a page I'm reading.

We use Confluence to do document reviews at work, and sitting there attempting to read a document while Confluence is popping up that annoying dialogue box over and over again as people comment on the doc is insanely annoying. With uBlock Origin I was able to (after a few false attempts) sniff the specific element and filter it out.