One plant I've researched for my puppy is Morning Glory. First, one needs to clarify leaves? flowers? seeds? And there are many varieties of vine called "Morning Glory", both annual and perennial.
Those of us of a certain age learned in high school to recite the specific varieties of annual morning glories whose seeds contained lysergic acid amide, offering the shortest path to synthesizing lysergic acid diethylamide, aka LSD. I recall Heavenly Blue and Pearly Gates. Other varieties are of less interest.
(I was banned from my high school chem lab, but not for LSD. A friend's brother researched short-acting hallucinogens too obscure to make illegal, and picked a relatively safe synthesis for us. He forgot to mention it would coat the lab in a white precipitate.)
That would be the morning glory described in the sketchy entry here. Yes, err on the side of caution, if convenient. If one has spent twenty years cultivating a shade wall of perennial morning glory, and the puppy chews the occasional leaf without swallowing, there's no cause to rip it all out.