Except, we have known for centuries that psylocibe is benign. The Nahua people in Mexico's Central Valley people have been using them for ceremonial purposes for centuries with no addictive side effects ever reported; its use even being described in Spanish colonial codices [0]. They are only "new" to the Western culture. In contrast, we have known for centuries that opioids are extremely addictive. [1]

[0] https://wikipedia.org/wiki/Psilocybe_aztecorum

[1] Look under History and look for Avicenna https://wikipedia.org/wiki/Opioid