AB:33:C6:C6:19:74
I used a MAC address generator to get those two, but I think two is enough to make the discussion. Current reality aside, would you be able to identify those with binary math as being on the same network device, different network devices, across the world? MAC addresses on physical NICs are provided by the manufacturer, sure you can adjust them but I think that leaves the good-faith portion of this discussion.
So if you wanted to have those to communicate no matter what you would have to have a network device state: "I'm network device A, I have this device 0C:F9:31:D2:DB:51" then another state: "I'm network device B, I have this device AB:33:C6:C6:19:74". Then whenever 0C:F9:31:D2:DB:51 wants to talk with AB:33:C6:C6:19:74 it's network device will have to just send it to the next upstream network device or if there are multiple network devices that could be upstream you could send it to them all which is just not great for security whatsoever or you now have to do a recursive lookup for whatever n devices might yet be upstream and wait for a response to see if one of those has it. Overall trying to send ethernet frames globally without an IP network sounds like not a great idea.