One thing that's always important to consider is that the relevance of anything is not fixed. The Nobel Prize is not seen as a grand achievement because it's the Nobel Prize, but because the scientific community, and society to a lesser degree, implicitly deems it such. When awards change, so does their relevance.

So rather than changing the Nobel Prize, it seems more logical to create a new prize. It doesn't seem like it should be that hard. I'm sure somebody like Bill Gates would just love to have his name attached to the 'Gates Prize for Collaborative Science' and he has the pockets to comfortably prefund it for a century.