Even normal collision avoidance systems cannot easily detect a semi truck sideways, because semi trucks and trailers in NA aren't required to have side skirts and protection bars. This won't happen in EU because all their trucks have mandated side skirts and bars. So when the car hits it the occupants are protected through the air bags and crumple zones.
The objective should be to prevent severe bodily harm or loss of life to the occupants in the event of a collision, with/without an avoidance system.
Find out why trucks in NA don't have mandated side skirts. Who's lobbying against it ?
If they really want to talk about lack of proper safeguards in autopilot they could've investigated many other reported scenarios like Teslas suddenly steering into the opposing lane, dividers. There are also reports of their system behaving erratically when the road slopes up into the horizon.