I'll happily agree that the limit is unknown and it might be higher than anyone expects - but at the current trajectory we're all going to find where it is as the US hits it face-to-wall-at-speed style. Years ago we crossed the limit where that debt was never going to be repaid in real terms. Now we're getting to levels where even the interest probably isn't going to be paid back in real terms.
And, in amongst this, it isn't really clear what the debate around science funding is supposed to look like. The US appears to be going broke. It'll probably struggle to find the money for big spending on science over the next few years. Even if they execute some sort of default they're still going to have to do a round of belt tightening.
Also - on Japan - topical news: https://marginalrevolution.com/marginalrevolution/2023/10/ja...
Waiting for more empirical evidence that this will break everything is not a great strategy. By the time the evidence is in, everything will be broken and the US will be deeply in debt. The US is already acting like an economic system under significant stress (prosperous people don't elect Trumps). When the dust settles it'll probably turn out that there were huge costs to the debt and they just didn't turn up as inflation (for example, if people literally can't afford something, then price inflation won't matter).
Japan having high debt and the US having high debt is no evidence at all that the US will end up like Japan. They've got completely different laws and people. Plus the median Japanese income is something like 80-60% of the median US income [1] so that is hardly an economic outcome to aim for.
[0] Started out with "Noy wanting to" but I figured that couldn't be true.
[1] https://worldpopulationreview.com/country-rankings/median-in...