With nonviolent crimes, such as drug abuse and financial crimes, I think the utility of incarceration depends on the degree to which the criminal might still be hurting society in nonviolent ways which would be prevented by incarceration. Maybe drug abuse is itself a victimless crime (I think there's room to disagree fwiw), in which case incapacitation via incarceration wouldn't be useful.
But I think you can't make that claim about financial criminals like Bankman-Fried or Bernie Madoff; these were not victimless crimes. They victimized many people, therefore putting them in prison for the rest of their lives is a fairly straight forward way of making sure they'll never get the opportunity to do it again.
> Not to mention any collateral damage such as the offender's family who may now also suffer and be drawn more towards conditions that would breed crime.
Particularly in the case of these two men, the damage to the offenders family is completely irrelevant; their families are wealthy and are probably beneficiaries of the crimes anyway, so screw their feelings. And it's not like Bankman-Fried has a young son that will grow up to be a criminal because his daddy is in prison. Elizabeth Holmes has some kids but I'm confident they'll be fine with their mother in prison; their father's family has plenty of resources to raise them properly. And what of the children of the victims of white collar crime, who will grow up poorer because their parents were scammed? This 'family impact' angle of objection to imprisonment for white collar crimes isn't very persuasive.