DAWs will need to refocus on managing recordings of live performances -- young kids are starting guitar bands again, and in a few years I think we will enter yet another period where electronic sounds are out of fashion.

I'd also like to see more music creation nuts & bolts built into DAWs, like integrated lyrics, a quick way to shuffle pieces of a song like "bridge" and "verse", visualizations of key center shifts, chord builders and so on. A lot of that stuff is out there but it's definitely an afterthought.