The pilots need oxygen masks as a backup while they quickly descend to a safer altitude. Unless you're flying over the Himalayas and can't drop that low, the passengers should be fine.
https://en.wikipedia.org/wiki/Emergency_oxygen_system#Incide...
Safety here being say; a user asking for instructions on how to make a dirty bomb and the model responds with "Sorry, I can't do that ethically".
In that sense it is mathematically equivalent to (say) applying an L2 regularization penalty to reduce the occurrance of higher-order terms when fitting a polynomial. Strictly it will produce a worse fit on your training data, however it is done because out of sample performance is important.
If not outright blocked, instructions do seem to be weighted down.
Given the self-evidence of no existential risk, there is then an objection to “dumbing down” where model performance suffers due to RLHF (the “alignment tax” is a real thing), and often but not always this includes an objection to wokeness or perceived unwillingness to speak “truths” or left-wing bias being imposed on models.