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Comment by Mistletoe | Hacker News Reader

It seems hard to believe the ethanol producing bacterial strain would dominate your oral microbione for life from one application. But I’m willing to have an open mind and see some data.

They need to get the data off of the Google drive and presented in a better way. I don’t click unknown Google drive links if I can avoid it.

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Brushing your teeth and using mouthwash wipes out the majority of the micro biome. Application of the new strain shortly after could totally replace it wholesale.

That said, I can’t imagine there’s not other side effects that just aren’t known yet. The sample size and reporting (as far as we know) is just too small and meaningless.

In one of their articles they claim that the microbiome is stable over 15 years, but this is categorized as "unpublished work" which leaves me with a large sense of doubt. I don't mind research that is in preliminary stages (as in conference abstracts, technical papers, etc), but the fact they are very naïve in how they approach scientific evidence makes me highly doubtful.

Does brushing and mouthwash really eliminate your microbiome? I heard it does precious little. Most of the microorganisms live below the gumline and surfaces. If that were true it would eliminate caries! Please post links

Mouthwash (WITH alcohol) daily almost completely eliminates the need for daily brushing and flossing. This was later retracted by demand of the ADA to only say "as good or better than flossing"; from here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894074/ "mouth rinses would be considered to be “at least as good as” daily flossing if the upper limit of the 90% confidence interval" there are a number of studies on this topic and they all seem to generally be in agreement. Mouthwash even once a week is really good for dental hygiene. They make alcohol free mouthwash but it's hard to argue with the antimicrobial properties of alcohol and the price difference is neglible.

No thanks. I'll not be using alcohol-based mouthwash. https://drugfree.org/drug-and-alcohol-news/australian-study-...

You should stop drinking diet soda too, a byproduct of metabolizing aspartame is formaldehyde which is also a carcinogen.

That would get rid of all the good bacteria too, which can't be… good.

This definitely can’t be true. There are too many spaces that cannot be reached mechanically.

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