Post George Floyd, I know mainstream moderate Democrats now that call the constitution a “racist document.” For longer than that, mainstream democrats have dismissed federalism as merely a pretext for segregation. People will regularly argue against adhering to the original meaning or intent of the document “because the founders were slave holders.”
Ideologically, the fact that the constitution represents a compromise with slave holders has become increasingly intolerable for democrats. Anti-racism as a principle has become more important than rule of law or cultivating a shared respect for the fundamental law.