Also, AFAIK these drugs always need to be taken continuously, if people stop taking them they return to whatever was their baseline levels. This can not seriously be seen as a good thing.
The experience of going through one whole day with only water/tea/coffee, feeling a hole in your stomach by early afternoon and seeing the hunger subside by bed time and lasting until the next afternoon also "demonstrate the disconnect between the desire and the need for food".
As far as taking them continuously, there are many chronic conditions that people take medication for life to resolve. For example high blood pressure, they put you on medication and its expected you will be on it for life, it isn't always solvable by any other means. Many other examples of chronic conditions which means ongoing medication must be taken.
What I think will be interesting is the higher order impacts to the major food companies. If enough people are on medication to disrupt the desire to eat sweets and highly processed foods, the incentive for the food companies is to try to find a way to bypass the effects of the medication.
I don't think it's true. Obesity increase hunger, prevent you to walk and/or exercise for long stretch of time (chaffed thighs, you don't want to experience it), and disturb your sleep which in turn increase your hunger.
It's easy to become obese when you're overweight and have bad eating habits, and it's very rare for people like me that were in very good shape at 18 to be clinically obese at 27 (it took a heart issue, then a badly broken ankle (4 years of rehab) to do it).
If the drug fix your food issues for 2 years, you're set imho.