Yes, but shouldn't some portability be sacrificed? Google Chrome, for example, has the same interface on OS X and Windows, but is fast and has a native feel on both platforms.
There's a vast, vast gap in the complexity of Chrome's ui and Photoshop's. I maintain an app with a cross-platform ui (Mac/Windows/*nix), and it adds an enormous amount of time re-doing everything on different platforms, particularly Mac.