I'd respectfully disagree. For the first part, datura is an anticholinergic neurotoxin, a deliriant. Salvia is a kappa-opioid dissociative, without any known toxicities. The important thing to keep in mind with salvia is minimalism. It has no tolerance to speak of, so nothing is lost by starting small, well smaller than you know will give noticeable effect. Then build up from there. (An effect of salvia overdose is 'automatic action', where your body moves on impulse without the intervention of your waking mind)