When I play games I turn off Music, and skip cut scenes, I want to play a game not watch a movie. If i want a movie I watch a movie...
the FPS I only leave on sounds required for the game, and most of the time I have my own music, youtube or some podcast on in the background as i am playing.
For non-FPS games, I turn off the sound completely.
I suspect my style of game play is more common that you would believe.
If voice actors disappears from gaming, I would not notice at all.