Big SUVs and pickup trucks are less or equally safe to mid-size SUVs and cars. The pickup frame is durable but doesn't provide good occupant protection. Also, big vehicles are more likely to crash being less maneuverable. Plus, a good portion of crashes are single-car and doesn't matter how big truck is if crash into pillar.
This is sadly untrue; larger vehicles are safer, and the largest are the safest. Legislation is the only way I can see to stop the vehicle size/weight arms race.