Cancer or not, perhaps it is also healthier for our brains to not constantly be tricked that they found a nice high calorie food item? It feels that it would become like food-tiktok, dopamine "addiction" etc. Sure, perhaps overweight people can benefit from sugar free alternatives temporarily as a remedy to lose weight.

Personally as someone who eats very clean and unprocessed, I like to take the sugar calorie consequence of sweet things I might eat like fruits and the occasional pastry or soda