Air pollution: down since the 1990s. [1][2][3]
Water pollution: down since the 1990s. [4][5]
Noise/light pollution: definitely up since the 1990s, agreed there.
Cancer: US deaths are way down since the 1990s, though it's cheating a bit since that was the top of the smoking-related spike in lung cancer. Still, other cancer deaths are way down since then too. [6][7] (Edit: worldwide this looks worse and things have increased lately, see: https://ourworldindata.org/grapher/number-of-people-with-can...)
Heart disease: can't find long term stats on this quickly, but cardiovascular mortality is way down. [8]
Obesity, addiction, and suicide: certainly up.
"Much worse environmental impact," I think the decline in air and water pollution makes this debatable.
Climate change is a bit of a weird one, because it's definitely getting worse, but at the same time, the worst-case scenarios (greenhouse gas emissions continue unabated into the indefinite future) is becoming less likely. [9] So the derivative is bad, but the second derivative is good.
[1] https://ourworldindata.org/grapher/death-rates-from-air-poll...
[2] https://www.slowboring.com/p/wildfires-have-partially-revers...
[3] https://ourworldindata.org/grapher/death-rates-from-air-poll...
[4] https://www.slowboring.com/p/the-good-news-on-americas-clean...
[5] https://ourworldindata.org/explorers/water-and-sanitation?ta...
[6] https://ourworldindata.org/grapher/cancer-death-rates-in-the...
[7] https://ourworldindata.org/grapher/cancer-death-rates?tab=ch...
[8] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268076/
[9] https://www.slowboring.com/p/people-need-to-hear-the-good-ne...