It is, in short, a degenerative process marked by the failure to perfectly maintain instruction sets for the creation and maintenance of structures that allowed for survival.
Reading that back it almost sounds political.
It is, in short, a degenerative process marked by the failure to perfectly maintain instruction sets for the creation and maintenance of structures that allowed for survival.
Reading that back it almost sounds political.
I don't think there is a scientific consensus on this particular mechanism as a root of aging. There is a lot of stuff happening along like epigenetic aging, accumulation of various toxins and seemingly pre-programmed atrophy of immune system in mammals.
The only de-aging experiment that demonstrated some positive results in humans didn't touch genes at all. It was the TRIIM and TRIIM-X trial which attempted to rejuvenate the thymus and thus reinvigorate immunity. The subjects exhibit a lot of changes consistent with being a bit younger (a few years).
Immune atrophy and toxic accumulation I would read as being the terminal effects of decreased functionality as a result of error accumulation, no?
https://www.lifespan.io/topic/why-we-age/
But there has been recent talk about adding five more:
https://www.lifespan.io/news/researchers-propose-five-new-ha...
Aging is complicated. Stuff like extracellular cross-linking of collagen through glycation cannot be reduced to genetic/epigenetic changes, and yet is obviously a huge problem for aged organisms.