Look, everyone likes epiphanies. If you're reading HN, you probably like them more than most people. I don't think this is a bad thing. Yes, it's important to be producing. Yes, you need feedback on your ideas from reality. But this is only true if we have ideas to begin with. The widely accepted startup methodology---start small and iterate---is just a process for generating epiphanies.
If we're "stumbling from one epiphany to another," we're not acting on them, or we only see part of the picture, or we just haven't gotten the right one yet. Despairing that rather than our methods, it's us that's broken is both unfounded (really? You've had every epiphany ever?) and unhelpful.
The girl in the comic is known to deploy cruelty for her own amusement; I think the author had excellent insight into the newbie pickup artist's mind, and gave his character a response calculated to strike at the core of the would-be Casanova's psyche.
Anyway, thanks for the post, OP.