Microsoft's split board keyboard mostly only-addresses the wrists. It does not deal with redirects, SFBs and doesn't eliminate stretching (keyboards that reduce the number of keys help with that).

QWERTY is an alternating layout. It wasn't designed for comfort. It was designed in the 19th century for a particular purpose that no longer exists (how many documents do you need to prepare that require a non-electric typewriter?)

Changing your keyboard layout does play a big role in relieving hand pain than just shelling out money for boards.