I haven’t seen a Blame! reference in the wild before! The concept of runaway AI that never stops building more infrastructure seems like one of those dystopian scenarios that is at least semi-plausible, and the idea that humans effectively lock themselves out of control by being too clever (net terminal gene) is just the cherry on top.
> runaway AI that never stops building more infrastructure
Try driving through Irvine, California some time and you will see it happening before your very eyes.