Except when it interferes with other software you install. I've inexplicably had many people unable to get Apache to serve PHP files from local folders that are synced to OneDrive. The only solution was to disable or uninstall OneDrive, which seemed to be installed by default.
whatinthe... who is installing Apache to serve files from a OneDrive-backed environment?!
Students with Windows machines who are learning web development. These devices are not serving pages publicly.