I know I being picky, but nuclear war is the only existential threat there.
It's unlikely that any pandemic would make humans go extinct. Covid showed that isolating population groups is possible, especially if bounded by water (Australia, new Zealand etc). Mass death sure, but not extinction.
Climate change will probably reduce livable spaces (although people already live in extremes like Alaska and Sahara) but humans are adaptable and certain parts will still be temperate. Again huge impact, but not existential.
Sure there's a lot of "other stuff" going on, but honestly it has always been thus. Two world wars for example caused several daily concerns for most of Europe, and much of Asia. Throw in revolutions in Russia and China, and independence for India, plus the technology booms, and life in 1950 was different to 1910.
I could write a whole comment on economics, but again a 2 year blip in inflation (it's down again now) is not going to end anything. Given the economic improvements in Asia over the past 50 years (China, S Korea, Japan, Vietnam etc) "most" of the world is better off than before. There's a long way to go, but its been an upward trend for a long time.