As an example, consider a user in Paris, and assume for the sake of this example that Cloudflare's closest POP is in Berlin. Assume that user visiting a site hosted by a French CDN, with POPs in both Paris and Berlin.
If that user tries to resolve cdn.mysite.fr via 1.1.1.1, they'd get a Berlin-based location, since the French CDN has no way of knowing that the user is actually closer to them, and Paris would have been the better option.