Why can none of the OS provide a simple everything-fuzzy-searchable interface with both directory and tag organization and sets to make the huge mess of poorly accessible configs they've created more palatable?
(by the way, is it possible to change settings within the OS via this search interface?)
Maybe you could use one with nix-darwin on OSX? Not sure.
Better starting point would be Group Policy, which is mostly a layer over the registry but containing pretty good descriptions of what a setting does. It has a Powershell module, so combining that with fzf and a preview pane which shows the description might ctually be pretty neat, but probably not very fast.
And it also lacks any visual cues, so if you're used to some icon in the main settings apps, you'll not see it in regedit