At that point, just build a MiSTer (FPGA-based reimplementation), then get or build an arcade cabinet adapter to have your MiSTer provide the brains.
Well, if you were to populate it with the chips from your old board, it would work. So as a replacement part if it was just your PCB that was cooked, it's not a terrible option. Just having the option to get such a brand-new ancient part is still valuable, regardless of cost.
On the bright side, I could spend $500 more on Mac Pro wheels.
And their site also states "These boards use the original bill of materials, follow the original schematics, and can be used to replace damaged original boards by using the original parts from these boards."
This is a link to some emulated 6502 cycle accurate units both using ARM or FPGA
You may need to do some Grievous Bodily Metalwork to make the screening can fit.
But you can still buy 6502 compatibles built on other technologies and processes, right? (Not sure if you can get them in DIP but still.) Differences in voltage levels are bound to cause changes, but jumping straight to emulation seems excessive (even if it’s probably actually easier).
Most of the TTL stuff is current manufacture, although you may need to adjust passive components used around "straight" TTL if you use modern 74HCT-family chips.
It's a piece of piss to build 1970s computers with cheap modern jellybean parts that Farnell keep in stock by the million.