TLDR; participants with cocaine history were administered caffeine IV. At high doses (300mg) they reported some mild euphoria, and a strange taste and/or smell.
Ask HN: aside from caffeine, what is the drug of choice around here?
Ask HN: aside from caffeine, what is the drug of choice around here?
Tangential details...
The 2018 hemp farm bill allows products to have up to 0.3% THC, but it took years for people to realize that gummies are hefty enough that 0.3% means a gummy can have 10-20mg of THC. So, at the ripe age of 57 I finally tried THC.
It was very frustrating because most of the good stuff I expected didn't happen: no euphoria, no munchies, no relaxation. I do get some of the negative things, like dry mouth. The one good thing I get is music enhancement, but only if I do it once a week or less (10-15mg). I've tried doing it more frequently and upping the dose to compensate, but nope: if I invoke the genie too frequently he refuses to come out of the bottle.
Food is totally unchanged for you? Wild! What about movies/tv?
Although I gone up to 25mg while I was experimenting to find a dose that works best for me, my target is 10mg. Maybe that isn't enough to trigger munchies.
Because the only thing I find it good for is music enhancement, I like to take a gummy around 9pm-10pm, then two hours later put on three albums with a particular kind of music, then hope that I get enhancement. If I'm feeling tired that day, though, I put it off because sucks to hit the sweet spot and then immediately fall asleep and not get to enjoy the music.
By enhancement, I mean I experience pronounced stereo separation and deeper notes seem to be very resonant. Sometimes I get little floaty and feel like I'm suspended in zero gravity while I drift to the music. Because I do it only once a week, I don't notice any disruption of my sleep.
EDIT: you asked about TV/movies. I don't watch them, so I don't know.
Thankfully it’s doesn’t cause any serious harm to you as far as drugs go.
I wonder though, about a 100 years ago, when weed was criminalised, it wasn’t just made illegal - people went out of their way to destroy and get rid of every single hemp plant they could find in nature. Across the whole globe no less. That’s quite a statement. Maybe that’s bound to happen again.
I did finally try a real joint -- of course it hits much faster, but the lung irritation and health concerns weren't worth it.
I'm a bit jealous of people who have a great time. A guy in the band I'm in is 45 and has been a daily smoker for 30 years. He is highly functioning -- has a good job, has kids -- and can work while high. I guess he knows exactly his response and does enough to feel good but not enough to cause problems. He also has a really high tolerance.
I'm kind of jealous of your friend. I've been a daily smoker before, and I'm usually able to like do simple tasks and such. But I just get too lazy and dysfunctional. And I feel dumber. Part of me is drawn to that because it's so much easier to be dumb. But I also depend on working memory to make a living and also for my favourite hobbies. Eventually I learned that the only thing that actually works is occasional use. I can't be completely abstinent because then I never actually learn moderation, and I just end up binging again. But if I know I can enjoy myself if I want to, I don't have to be constantly thinking "fuck I want some weed". And then when I do finally give in, there's this shame spiral about it that leads to binging. Whereas now I can just smoke if I feel like it, have a great night of sleep and go on with my life the next day.
Watching my brother destroy his life with Heroin has kept me away from opioids for the most part, but I don't like the way they make me feel anyway.
Wow writing that all out makes me look like a degenerate :)
Had some funny experiments in there but would never go back to nothing. It doesn't make sense, especially if you don't have an addictive personality & any chemical risk is more likely associated with quitting beneficial chemicals than staying on them too long.
Wellbutrin (NDRI) every morning. Helps with attention and alertness. It isn't classified as a stimulant, so I don't need to deal with the regulations around regular ADHD meds. It also helps with sexual dysfunction caused by other meds.
Benzos for social events. Way better than alcohol. All of the chill and none of the impairment. :)
What's the equivalent of a 300mg IV dose in oral ingestion?