I attended a conference in Portland in 2022. The conference itself was fine, but Portland was a wreck. There were homeless encampments all over the place, open fires right on the sidewalks, needles and trash all over the place, boarded up buildings right in the middle of downtown. It was just bizarre and I felt pretty uncomfortable unless I was walking with other people.
I don't see why anyone would choose Portland as a conference location now. The city is in really bad shape, it's just not the same place it was even just a few years ago.