So what if you redo your experiment with lower positive-pressure flows? This is:
1. Keep the 280-m^3/hr purifier on the whole time.
2. Start with the 220-m^3/hr positive-pressure system running.
3. Wait for the particulate-level to equilibrate, then record the particulate-level and the pressure-difference (between outside and inside).
4. Reduce the air-flow of the positive-pressure system by, say, 20-m^3/hr.
5. Loop back to Step-3 while the air-flow of the positive-pressure system isn't negative.
With the objective to be to determine how low the positive-pressure system's flowrate can get while still maintaining its benefits, reducing heating/cooling losses.