SQLite could scale to even quite large customers with this.
Another really compelling architecture is a DB per user, with partial/selective sync between the nodes. If you then couple this with a "local first" design, the "edge" just becomes an other local deployment that the users db can sync against. Collaborative apps, where the users have their own documents but can also share/fork them would align well with this.
I believe starting with "local first" and using the edge for sync and "online only" modes is going to become the default for a significant number of apps moving forward. SQLite with CRDT based syncing and merge conflict resolution is the way to do this. There are a couple of exciting projects working on this: