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DigitalOcean had a nice blog post on this "From 15,000 database connections to under 100: DigitalOcean's tale of tech debt" https://www.digitalocean.com/blog/from-15-000-database-conne... they used MySQL as a message queue and migrated from it.

> ...it was simple and it worked – especially for a short-staffed technical team facing tight deadlines and a rapidly increasing user base.

> For four years, the database message queue formed the backbone of DigitalOcean’s technology stack.

The lesson I got from that article is that a database messaging system got them very far and was simple.