It depends on a lot of factors. Many older homes today were converted from barns and other structures that were not designed to optimize climate.
But some homes were indeed designed with climate in mind. The broad rear side might face the south to be heated during winter. The whole house may be configured with one long hallway with windows or screen doors at either end to allow cross breeze. Windows on different floors may be designed to open part way to facilitate cross breeze. The fire place may be located deeper in the house near the bedroom, with subsequent rooms getting farther from the fire so in winter you can shut the doors and only heat your own room with the one fireplace.
An attic fan that can switch between blow and suck is essential to keep cool (and prevent mold using air flow). When it's cool in the early mornings, keep windows open to cool the house, then close them when the sun rises and close shutters. As the temps rise throughout the day, you crack a window upstairs and turn on a window fan (blowing inward) and one window downstairs (blowing outward) to create a downward breeze, or the reverse to pump heat up and out.
My ex hasn't owned an AC in 10 years. She just regulates the doors and windows and has window fans. House is 130 years old