It's not an insurmountable barrier, for sure. Just something that makes it very annoying in a lot of code. While not really making it easier anywhere.
Not really when the code is routinely transcribed from papers, and the ages-old convention throughout mathematics is one-based indexing, both bounds of the interval included. (With the notable exception of Euler’s beta and gamma functions.) Of course, in a paper intended for a human reader the occasional off-by-one error is much less dire than in code, so the author is freer to use a more error-prone convention.
I once had to translate from a one-based paper to zero-based Python code (with the added bonus of different discrete Fourier conventions *shudder*), and it’s remarkably annoying even if the resulting code is more obviously correct than the paper’s original formulas.