Depends what you mean by "little things". If it's "a little thing that happened", then absolutely. If it's "a little thing that happens regularly", then it's worth discussing it before it snowballs.
OP sounded more like the first; something ongoing, sure.
To me it felt like "every little thing," but that was due to a combination of me being defensive + not seeing the value in communication and preventing resentment. Today I'd consider many of those little things to be important.