DHH, I think you misunderstood here; I believe Jeremy's referring to the blog post where you said Basecamp Next had almost as many lines of CoffeeScript as lines of Ruby. I think that's where the 50/50 number came from.
I'm less curious about the performance here than I am about the maintainability. I saw a tweet where somebody said he'd done things the same way and encountered a maintenance nightmare -- he mentioned nested caching and pjax specifically -- but without context or detail, I'm taking that with a grain of salt. I think disregarding it completely would be a mistake too, though.
It's also kind of tautological that DHH is going to have a more pleasant experience developing in Rails than he is in other frameworks. ;-)