I didn't read earlier about the backlash, but yes, I was talking about these-https://www.bbc.com/news/health-63749586

But I see there are side effects as well (Thanks for pointing it out) -https://www.axios.com/2023/05/15/alzheimers-drugs-patients-r... -https://www.science.org/content/article/scientists-tie-third...

It's good then that we now have another solution to tackle this like mentioned in OP, such as targeting reelin or APOE. And if anti-amyloids, or reducing amyloids are only a part solution. Hopefully, the findings keep continuing to cure Alzheimers.