While I was there, we switched over from Alpha to Intel because the performance just wasn't there on Alpha - IIRC the 75MHz Intels blew the 233MHz Alphas out of the water. Most of us chalked it up to the fact that Microsoft wasn't super interested or able to optimize Windows to run on Alpha.
As sort of a "stunt" I got the newer versions of the Multia software that were only available on Intel to run on the old Alpha Multias under a (then internal project) emulator called FX!32