Hacker News Reader

Weakening the immune system is not an uncommon property of viruses and Coronaviruses are know to not engender long term, durable immunity. So, with COVID, what we have is not “special powers,” but a combination of both qualities in a more (at the population-level) virulent disease. Natural immunity for COVID works pretty much the same as it does for other Coronaviruses (you can get the same one multiple times per year), but that’s problematic given the disease’s overall severity and propensity to damage people’s immune systems in a way that makes them susceptible to other illnesses (see the recent spate of post-COVID fungal infections).

Dengue is such a virus: repeated infections get worse.

Quoting: 'repeated infections over-sensitize the immune system, almost like an allergic reaction or something."

Try the 'R' in the (Strain-) Sequency (RRRRR) maybe it matches your thought (not an expert...) regards...