Datomic is an operational database management system - designed for transactional, domain-specific data. It is not designed to be a data warehouse, nor a high-churn high-throughput system (such as a time-series database or log store).
It is a good fit for systems that store valuable information of record, require developer and operational flexibility, need history and audit capabilities, and require read scalability.
(via https://docs.datomic.com/pro/getting-started/brief-overview....)