It'd be nice if the browsers could adopt a standard prefix for experimental styles (-exp- maybe) which is then replaced by the browser prefix before being used - so in Chrome -exp-text-size-adjust would become -webkit-text-size-adjust and in Firefox it would become -moz-text-size-adjust. That way we can escape the necessity of doing one rule for each prefix (-webkit- -moz- -o- -ms- etc.) and just have one. Browsers could just ignore the rules which they haven't implemented yet and web devs would not be able to cause problems by targeting just one family of browsers.
It could probably be implemented by a quick text replace before parsing (the c++ equivalent of s/-exp-/-webkit-/g) and would shrink the size of some stylesheets considerably.