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...but then the difficulty of quitting Vim becomes a feature. Can't crash the system by exiting, if you can't exit (taps head meaningfully). /s

Execute tmux using vim shell command. Kill -9 vim

/worth a shot?

PID 1 is special and can not be killed with signal 9 for security reasons. See kill(2).

lol, the nuclear option. You don't mess around, but really, I think the answer is, never quit Vim.