A split keyboard has been an excellent change for me, but it doesn't have to come with other changes such as unusual layout or orthogonal.

I went for Mistel Barocco. Its basically a normal layout but split down the middle.

Took almost zero time to get used to, as its basically a normal keyboard. The benefits of things like orthogonal layout seem questionable to me, but the split layout gives me an overall much more comfortable position at a desk.