I don't know Manhattan very well, only what I've seen on TV and in Movies.
Back of napkin answer:
Build bigger buildings, lots of them. All of those 'quaint' places with 2-6 story buildings? 50-60+ story sky-scrapers.
However that's probably also the answer you assumed. Yes that would change the 'character' of a place, because the only way of keeping that the same is to keep the number and type of people in a place the same. How could someone preserve an idea that directly contradicts a reality? No, there would need to be a new idea that supports the desired conditions. Hopefully a good idea that is well executed.
As another commenter said, 'more ''Manhattans''' is another way, try to replicate the sort of feel / idea at existing scale or larger in other locations.
My own comment was about the technical and physical goals a society should strive for, which are within reach, should we the people have the will to reach for them.